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Big Brother Australia 2006 was the sixth series of Big Brother Australia tv show , it was aired on Network Ten in Australi with the series beginning on April 22, 2006 and finishing on July 31, 2006; running for a duration of 101 days.

In the auditions which were held in November and December of 2005,The producers had asked for contestants who were "smart, strong, and looking for a fight". Launch was aired on the evening of April 23, 2006. On day 0 Fifteen housemates initially entered the house, with the additional three Intruder housemates entering the Big Brother House in Week 4, another three Intruders in Week 9, and during week 12 two replacement housemates entered

On Day 100, Jamie was declared the winner of Big Brother 2006, with Camilla the runner-up. At the time it was the closest winning margin in any Australian series of the show, later beaten by Series 7.

This season had the infamous "Turkey slap" incident. An alleged sexual assault during which John (real name Michael Bric) held down Camilla Severi on her bed while Ashley (Michael Cox) pushed his crotch into her face. Resulting in the disqualification of the two men. The incident sparked calls for the series to be investigated for possible breaches of broadcasting laws, and calls for the cancellation of the series by several commentators and politicians, including Australian Prime Minister John Howard and opposition leader Kim Beazley.